Scientist (m/f/d) Functional Assay

Glycothera is a specialized CDMO supporting biologics development across cell line development, process development, analytics, and GMP-aligned testing. Operating from integrated sites in Julich and Hanover, Germany, the company works within a unified scientific and quality framework that enables reliable, regulatory-ready CMC execution. With nearly three decades of development experience and long-standing contributions to biologics supported by EMA and FDA approvals, Glycothera partners with biotech and pharmaceutical companies to advance development programs with scientific depth, precision, and consistency.

• Perform, evaluate and document experiments for method development of functional assays, including cell-based assays (e.g. potency, CDC, ADCC, ADCP, apoptosis assay, proliferation assay) and binding assays (e.g. Biacore/SPR) according to ICH guidelines.
• Handle cell lines and primary cells (e.g. isolation, freezing, thawing, propagation, testing).
• Analyze samples to support the development of therapeutic candidates across various departments/process steps.
• Perform, evaluate and document functional assays for analytical similarity and comparability studies.
• Draft regulatory documents, including SOPs, R&D-Procedures and development reports.
• Support method validation and method transfer activities.
  • Take care of laboratory equipment (e.g., perform instrument maintenance and qualification) and support laboratory management tasks.
  • The role will be primarily lab-based.

• B.Sc. in relevant scientific discipline (life sciences such as biology, biomedical sciences, biochemistry, biotechnology, etc.) with minimum 3-5 years of relevant work experience, or M.Sc. with 1-2 years of relevant work experience.
• Experience working with mammalian cell lines under aseptic conditions, including culture initiation, propagation and cryopreservation is a must. Separation and purification of primary human cells is a plus.
• Experience with potency and bioassay development (e.g., CDC, ADCC, proliferation, apoptosis) for monoclonal antibody analysis is required. Experience with other modalities is a plus.
• Experience with relevant analytical methods (e.g., ELISA formats, Flow Cytometry) is required.
• Experience with biochemical and biophysical methods for binding characterization (e.g., Biacore/SPR) is advantageous.
• Attention to detail and precise work habits.
• Excellent written and verbal communication skills.
• Proficient in using a PC and common Microsoft packages. Experience with specific laboratory instrumentation (e.g., Biacore T200 and 8K, MSD, Flow cytometer, microplate reader) and analysis software (e.g., SoftMax, Methodical Mind, MACSQuantify, Biacore Insight) is a plus.

We look forward to receiving your complete application (cover letter, CV, relevant references), including your earliest possible start date. Please submit your documents through our online portal.

We welcome applications from all individuals, regardless of gender, age, background, or disability.